Sorry for creating a separate thread, but there are so many threads about this topic already... I recently upgraded the operating system on my hp tx2500 tablet pc (tx2524ca) from 64bit Vista Home Premium (+ Bloatware) to 64bit Windows 7 Professional. Can't recommend it highly enough. But... like a lot of people I lost pressure sensitivity in Photoshop (32bit CS5, 64bit CS5, 32bit Elements2, don't laugh) & OpenCanvas4.5ePlus, although not in MS Office 2007 or pen tablet input. tx2500 series have Wacom TabletPC Digitizer, so that appeared to be the issue. I tried pretty much everything i could find on the web, nothing worked. until... ...basically I found the solution on this thread here, full credit goes to "Wacom" and "animation_nerd", i'm gonna copy and paste but with a few of my additions: Wacom Forum - Wacom Europe GmbH • View topic - HP 2730p 32 bit app pressure SOLVED: What I did: Clean install of Windows 7 64bit Leave all installed pen and tablet drivers untouched in device manager (don't need to disable or delete) download most up-to-date TabletPC Driver. US site is: Wacom Hardware Drivers Europe-English site is: Wacom Europe GmbH - Support - Driver as of present, most current driver version is 126.96.36.199 (Date= 02-Nov-2010). name of file is isd701-8_int.exe or ISD_DualTouch_701-8.exe depending on site downloaded from. but wacom continually updates it Install tabletpc driver. Restart. But... apparantly "the installer does not install the proper dll's in C:\Windows\SysWOW64, It only installs the 64 bit driver in there." So, unzip the Driver package. to do this, I copied and pasted the driver download package file, renamed extension from .exe to .zip, then unzipped the driver package Locate 2 files in ISD_DualTouch_701-8\System32\64\32\ (ISD_Tablet.dll,Wintab32.dll) copy and paste these 2 files into to C:\Windows\SysWOW64\ (I archived the existing Wintab32.dll, it appeared to be the version of the file located in ISD_DualTouch_701-8\System32\64 -apparently you can't have both versions present???) -Restart -Pressure sensitivity restored!!! Happy Photoshopping!!!! All my pressure sensitivity seems to be restored. Note that I have disabled the touch function on my screen (it interfered with my pen use) so I can't comment if it works or not.